JUVÉDERM® Ultra 3 is a top-tier, clinically proven hyaluronic acid (HA) dermal filler designed for medium-to-deep facial wrinkle correction, precise facial contouring, and subtle lip volumization. Developed by Allergan Aesthetics, a global leader in aesthetic medical solutions, this injectable gel combines advanced cross-linking technology with a user-friendly, comfort-focused formulation to deliver instant, smooth, and natural-looking anti-aging results. Tailored for aesthetic practitioners and ideal for diverse patient needs, JUVÉDERM® Ultra 3 balances outstanding durability, soft tissue integration, and minimal downtime, making it a staple in professional facial rejuvenation treatments worldwide.
Formulated with non-animal, highly purified cross-linked hyaluronic acid at a concentration of 24 mg/ml, the product features a homogeneous, cohesive monophasic gel structure that adapts seamlessly to facial tissue movement. Infused with 0.3% lidocaine hydrochloride, it significantly reduces injection discomfort, ensuring a gentle treatment experience for patients while maintaining superior moldability for precise practitioner application.
Core Technology & Formulation Excellence
JUVÉDERM® Ultra 3 leverages the proprietary Hylacross™ technology, a cutting-edge cross-linking process that creates a uniform, elastic, and robust HA gel matrix. Unlike conventional fillers with inconsistent particle structures, the Hylacross™ manufacturing method eliminates irregularities, producing a smooth, malleable gel that offers dual benefits: exceptional structural support for wrinkle correction and soft, natural flexibility that mimics native human skin tissue.
Key formulation attributes include:
Biocompatible & Non-Animal HA: Sourced from microbial fermentation, the hyaluronic acid is 100% synthetic, eliminating the risk of animal-derived contaminants and minimizing allergic reaction risks. It is fully biodegradable and naturally metabolized by the human body for safe, temporary results.
Integrated Lidocaine (0.3%): The pre-mixed local anesthetic numbs the treatment area during injections, drastically reducing pain, stinging, and post-injection tenderness. This built-in comfort feature streamlines treatment procedures and improves overall patient satisfaction.
Optimized Gel Cohesion & Viscosity: The balanced viscosity allows the gel to stay precisely in the targeted injection zone without migration, while its cohesive structure resists breakdown and maintains long-term volumizing and smoothing effects.
Stable Sterile Formula: Supplied in pre-sterilized, ready-to-use syringes, the phosphate-buffered gel maintains pH balance and molecular stability, ensuring consistent performance and safety for every treatment.
Primary Treatment Indications
Versatile and multi-functional, JUVÉDERM® Ultra 3 is engineered to address common signs of facial aging and enhance facial aesthetics with subtle, non-overdone results. It is specifically indicated for the following professional aesthetic treatments:
1. Correction of Medium to Deep Facial Wrinkles & Folds
Effectively smooths moderate to severe static facial lines, including prominent nasolabial folds (smile lines), marionette lines extending from the mouth corners, and perioral wrinkles. The gel fills depleted dermal tissue volume, erases deep creases, and restores a smooth, youthful skin texture without creating a stiff or overfilled appearance.
2. Lip Contouring & Subtle Lip Volumization
Ideal for patients seeking natural lip enhancement rather than exaggerated volume. JUVÉDERM® Ultra 3 precisely defines lip borders, corrects asymmetrical lip contours, adds gentle fullness to thin lips, and improves lip hydration and plumpness. The soft gel texture ensures lips remain supple and movable, maintaining natural facial expressions during speaking and smiling.
3. Facial Soft Tissue Volumization & Contour Refinement
The filler replenishes age-related volume loss in key mid-face and lower-face areas, refining overall facial harmony. It subtly lifts sagging soft tissue, balances uneven facial contours, and rejuvenates a tired, dull facial complexion for a refreshed, youthful look.
Key Product Benefits
Instant & Natural Results: Visible smoothing, volumization, and contour improvement appear immediately after injection. Results blend naturally with existing facial features, avoiding artificial or over-augmented looks.
Long-Lasting Duration: Treatments deliver consistent, stable results for up to 12 months after injection. The cross-linked HA matrix resists rapid degradation, extending the rejuvenation effect while allowing gradual, natural fading.
Minimally Invasive & Low Downtime: As a non-surgical injectable treatment, it requires no incisions or general anesthesia. Most patients experience only mild, temporary redness, swelling, or bruising that resolves within 24–72 hours, with minimal disruption to daily life.
Superior Patient Comfort: Pre-blended lidocaine eliminates the need for separate numbing injections, simplifying treatment workflows and delivering a pain-free, comfortable experience.
High Safety & Low Reaction Risk: Non-animal HA formulation delivers exceptional biocompatibility. Allergic reactions, inflammation, and rejection risks are extremely low, making it suitable for most skin types and patient demographics.
Practitioner-Friendly Application: The smooth, low-resistance gel enables effortless, precise injection and molding. It holds shape reliably post-application and does not migrate, allowing practitioners to achieve symmetrical, customized results for every patient.
Product Specifications & Packaging
Active Ingredient: 24 mg/ml non-animal cross-linked hyaluronic acid
Anesthetic Component: 0.3% Lidocaine Hydrochloride
Technology: Hylacross™ Cross-Linking Technology
Standard Packaging: 2 x 1.0 ml pre-filled sterile syringes per box
Consistency: Smooth, homogeneous, cohesive monophasic gel
Duration of Results: Up to 12 months (individual results vary by skin condition, treatment area, and lifestyle)
Metabolism: Fully biodegradable, naturally broken down and excreted by the human body
Safety & Professional Use Guidelines
JUVÉDERM® Ultra 3 is a professional medical-grade dermal filler intendedexclusively for licensed and trained aesthetic practitioners. All injection procedures must be performed in a sterile clinical setting to ensure patient safety and treatment efficacy.
General safety notes:
Avoid use for patients with known allergies to hyaluronic acid, lidocaine, or any product ingredients.
Not suitable for injection into blood vessels, bony areas, or superficial epidermal layers.
Temporary mild side effects including redness, swelling, bruising, itching, or slight tenderness at the injection site are common and self-resolving.
Patients should avoid strenuous exercise, excessive sun exposure, and facial pressure for 24–48 hours post-treatment to optimize results.
Why Choose JUVÉDERM® Ultra 3?
Trusted by aesthetic professionals across the globe, JUVÉDERM® Ultra 3 stands out in the competitive dermal filler market for its perfect balance of safety, performance, and versatility. Its unique gel formulation delivers reliable, long-lasting anti-aging results while prioritizing patient comfort and natural aesthetic outcomes. Whether for wrinkle correction, lip enhancement, or facial contour refinement, this premium filler offers customizable solutions to address diverse aging concerns, helping patients restore youthful radiance and confidence with minimal risk and maximum satisfaction.
