Is Hyaluronic Acid Dissolving Enzyme A "remedy" for Hyaluronic Acid Poisoning?

Dissolving enzymes are often used for repair after hyaluronic acid injections. Because they can repair, they are also called the "regret medicine" for hyaluronic acid. But is this really the case?

What is Hyaluronidase?

Hyaluronidase, also known as hyaluronidase or "injectable hyaluronidase," is an enzyme that hydrolyzes hyaluronic acid. It is a natural enzyme that hydrolyzes hyaluronic acid and is primarily used to repair failed hyaluronic acid injections, remove injected material from unsuitable sites, and eliminate lumps caused by excessive hyaluronic acid injections, achieving a 90% elimination rate.

Note 1: A skin test is required for every injection of lysozyme.

Many patients who come for lysozyme injections are confused: they've had lysozyme injections before without any allergic reaction, so why do they need to have a skin test again? It's important to note that a skin test is required before each lysozyme injection because the sensitization rate varies from batch to batch. For safety, a skin test is necessary every time.

Note 2: The amount of hyaluronic acid that the doctor intends to dissolve is uncontrollable.

Hyaluronic acid is particulate; wherever it's injected, it provides support. But what about hyaluronic acid? Think of it this way: for example, if three syringes of hyaluronic acid are injected into the chin, and the doctor uses about one syringe of hyaluronic acid to refine the shape and lines of the chin, injecting the hyaluronic acid into the upper part of the chin to refine that area. However, because hyaluronic acid is liquid, it will flow downwards after injection, so there's no guarantee it won't affect the shape of the lower parts. Therefore, the immediate effect of hyaluronic acid during the procedure is relatively uncontrollable, unlike the precision of hyaluronic acid, where injecting 0.2g can produce 0.2g of the desired effect.

Another issue is the injection depth.

Simply put, the hyaluronic acid needs to meet the dissolving enzyme for the hyaluronic acid to be dissolved into water and metabolized by the body. If they don't meet, the desired effect cannot be achieved. For example, if a patient receives hyaluronic acid injections from one doctor and later receives dissolving enzyme injections from different doctors, with one doctor injecting at a deeper level and the other at a superficial level, the two won't meet, and the hyaluronic acid won't dissolve. Therefore, the effect of dissolving enzyme injections is not entirely controllable.

When using hyaluronic acid dissolving enzymes for facial contouring, we can only inject and dissolve them little by little, gradually approaching the desired degree. This is because if too much is dissolved, the doctor doesn't have the reserve of hyaluronic acid to replenish it. Hyaluronic acid dissolving enzymes are bottled and prepared; after opening, they are mixed into a solution before injection. Hyaluronic acid, on the other hand, is used in single vials, making it impossible to inject small amounts into the face.

Note 3: Hyaluronic acid cannot be injected on the same day as hyaluronidase injection.

It is unscientific to inject hyaluronidase and hyaluronic acid into the same area at the same time. We generally recommend an interval of at least three days (preferably more than seven days) before proceeding.

Note 4: There are certain risks associated with injecting hyaluronidase.

First, the injection site for hyaluronidase must not have swelling or infection before the injection. If these conditions exist, it can lead to severe swelling and the risk of infection spreading. Second, the injected product must be hyaluronic acid. Injecting hyaluronidase with other materials is meaningless.